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Pirfenidone Reduces Respiratory-related Hospitalizations in Idiopathic Pulmonary Fibrosis In a pooled analysis of three phase 3 IPF clinical trials, patients receiving pirfenidone had a lower risk of non-elective respiratory-related hospitalization over 1 year. Among those hospitalized for any reason, pirfenidone was associated with a lower risk of death following hospital admission.
Fleischner Society Guideline Update 2017: Management of Solid Pulmonary Nodules. Updated 2017 Fleischner Society guidelines advise a less intensive approach to the management of most small pulmonary nodules incidentally discovered on CT scans. The Fleischner Society now recommends that solid nodules 6 mm or less in diameter in low-risk adults >35 years old generally need no further follow-up. In higher-risk patients, a follow-up CT scan should be considered optional. The recommendations apply even if multiple solid pulmonary nodules ≤6 mm are present.
Reduced COPD exacerbation risk correlates with improved FEV1: A meta-regression analysis. A significant correlation between increased FEV1 and lower COPD exacerbation risk suggests airway patency is an important mechanism responsible for this effect
Sleep apnoea and risk of post-operative infection: beyond cardiovascular impact. the risk of pneumonia or sepsis is more than doubled in patients with a predominance of central, rather than obstructive, respiratory events
Waist circumference a better indicator of health than BMI is a better indicator of increased risk of death from cardiovascular causes or any cause.